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Abstract #0729

Quantitative Analysis of Arterial Phase Transient Respiratory Motions Induced by Two Contrast Agents for Dynamic Liver MR Imaging

Yuxi Pang1, Dariya Malyarenko1, Matthew Davenport1, Hero Hussain1, and Thomas Chenevert1

1Department of Radiology, UNIVERSITY OF MICHIGAN, ANN ARBOR, MI, United States

This work is to analyze the respiratory waveforms from dynamic liver MR images related to the motion artifacts in arterial phase images induced by the contrast-media administration. The discriminative metrics were defined to quantify the likelihood of the acutely and temporally impaired breath-holding by the subjects who received gadoxetate disodium and gadobenate dimeglumine contrast agents. Our preliminary results show that the indicative metrics derived from recorded respiratory waveforms objectively confirm prior reported observations that gadoxetate disodium has a significantly higher likelihood of inducing acute transient breath-holding difficulties that adversely affect arterial phase image quality.

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