1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, 2Philips Healthcare, Guangzhou, China, People's Republic of, 3Philips Healthcare, HongKong, China, People's Republic of
In human brain, T1ρ
has been proven to be relevant with the macromolecular composition of tissues,
and supposed to be sensitive to neuronal degeneration. We used T1rho MR imaging
to investigate the variations in T1rho values of subcortical gray matter
structures automatic-drawn using FIRST segmentation among temporal lobe
epilepsy patients and the underlying relation between the significantly altered
T1rho values or volumes of subcortical structures and duration of epilepsy or
age at epilepsy onset. Our results demonstrate the feasibility of ROI-wise
analysis by atlas-based segmentation of T1rho imaging among mTLE patients
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