Jeroen Mollink1,2, Michiel Kleinnijenhuis1, Stamatios N Sotiropoulos1, Michiel Cottaar1, Anne-Marie van Cappellen van Walsum2, Menuka Pallebage Gamarallage3, Olaf Ansorge3, Saad Jbabdi1, and Karla L Miller1
1FMRIB centre, University of Oxford, Oxford, United Kingdom, 2Donders Institute for Brain, Cognition and Behaviour, Department of Anatomy, Radboud University Medical Centre, Nijmegen, Netherlands, 3Department of Neuropathology, University of Oxford, Oxford, United Kingdom
In this study we explored fibre orientation dispersion in the corpus callosum using diffusion-weighted MRI, Polarized Light Imaging and Histology.
fibre orientations were derived from Polarized Light Imaging and
histological myelin and glial cell staining, with the aim of understanding the
microstructural features that correlate with the diffusion signal.