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Abstract #0819

Non-invasive cardiac stimulation with MR guided HIFU: a rapid, cardiac triggered, MR-ARFI method for direct visualization of stimulation site and assessment of tissue stiffness.

Pierre Bour1,2, Fabrice Marquet2, Fanny Vaillant2, Valery Ozenne2, Solenn Toupin2,3, Matthieu Lepetit coiffe3, Erik Dumont1, and Bruno Quesson2

1IGT, PESSAC, France, 2IHU-LIRYC, PESSAC, France, 3Siemens Healthcare, Saint-Denis, France

HIFU cardiac stimulation may enable diagnostic and therapeutic applications such as noninvasive electrophysiological exam, emergency care and temporary stimulation. In-vivo proof of concept of HIFU cardiac stimulation has already been done on pig. We propose here a first proof of feasibility to monitor the displacement induced by acoustic radiation force impulse (MR-ARFI) during contactless stimulation ex-vivo, on a beating pig heart model. ARFI displacement maps will be used for precise localization of the depolarization source and a quantification of displacement will be done during refractory (contraction) and non-refractory (resting time) period.

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