1Medical Imaging, Jingling Hospital, School of Medicine, Nanjing University, Nanjing, China, People's Republic of, 2GE Healthcare, MR Research China, Beijing, China, People's Republic of
Diffusion-weighted imaging (DWI) in human transplantation was regarded as a
promising indicator for dectecting graft dysfunction.According to the IVIM
theory, ADC integrates the effects of both diffusion of water molecules and
microcirculation of blood in capillaries. By separating diffusion and
perfusion, we could observe each component’s contribution to the changes of ADC
values. Furthermore, the exchanges of intracellular water molecules with
extracellular’s may have impact on ADC. Thus, AQP ADC might reflect quantitative
water channel expression.
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