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Abstract #0837

NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer

Yan Lin1, Changchun Ma2, Zhening Wang1, Zhiwei Shen1, and Renhua Wu1

1Radiology Department, Second Affiliated Hospital, Shantou University Medical College, Shantou City, China, People's Republic of, 2Radiation Oncology, Cancer Hospital, Shantou University Medical College, Shantou City, China, People's Republic of

Colorectal cancer (CRC) is a growing cause of mortality in developing countries, warranting investigation into its earlier detection for optimal disease management.This study aimed to validate the ability of NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in CRC patients.Our findings revealed that the fecal metabolic profiles of healthy controls can be distinguished from CRC patients, even in the early stage (stage I/II), highlighting the potential utility of NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in CRC patients.

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