Yoann Petibon1, Behzad Ebrahimi1, Timothy G Reese1,2, Nicolas Guehl1, Marc D Normandin1, Nathaniel M Alpert1, Georges El Fakhri1, and Jinsong Ouyang1
1Center for Advanced Medical Imaging Sciences, Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, 2Athinoula A. Martinos Center, Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States
PET imaging enables absolute quantification of myocardial blood flow (MBF).
However, motion of the heart during imaging deteriorates the accuracy of PET
MBF measurements. Simultaneous MR/PET makes it possible to compensate PET
images for motion by incorporating MR-based motion information inside the PET
reconstruction process. In this study, we propose and assess the impact of a tagged-MRI
based PET motion-correction technique for improved PET MBF quantification using
an in-vivo simultaneous MR/PET study.