Akimasa Yamada1, Masaki Ishida1, Takashi Ichihara2, Takahiro Natsume2, Yoshitaka Goto1, Mio Uno1, Motonori Nagata1, Yasutaka Ichikawa1, Kakuya Kitagawa1, and Hajime Sakuma1
1Radiology, Mie University Hospital, Tsu-Mie, Japan, 2Faculty of Radiological Technology, Fujita Health University School of Health Science, Toyoake-Aichi, Japan
In this study, we proposed a new method that synergistically
analyzes quantitative perfusion MRI and T1-mapping for quantifying k2, as well
as K1, myocardial blood flow, lambda and extracellular volume fraction.
Nineteen patients with previous myocardial infarction (MI) were studied.
Myocardial segments were categorized into 3 groups by presence or absence as
well as severity of MI in each segment. Quantitative measurement was successful
in all segments with significant difference among the 3 groups of myocardial
segments for all tissue kinetic parameters including k2. Synergistic assessment
of quantitative perfusion MRI and T1-mapping is promising for more detailed
myocardial tissue characterization.