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Abstract #1000

Automatic adaption of ASL labeling parameters: Walsh-sorted time-encoded pCASL with a dynamic feedback algorithm

Nora-Josefin Breutigam1, Federico von Samson-Himmelstjerna1, and Matthias G√ľnther1

1MR Physics, Fraunhofer MEVIS, Bremen, Germany

A dynamic feedback algorithm to find the optimal free-lunch (FL) bolus-length in a multi-TI Hadamard-encoding scheme is presented. An estimated FL bolus-length is often not ideal for the examined subject. In arterial spin labeling (ASL) this frequently results in unwanted arterial transit-delay (ATD) artefacts. The proposed method allows approaching the optimal FL bolus-length individually by analyzing intermediate decoded perfusion-weighted images during a running MRI scan. The aim is to reduce the FL bolus-length as much as necessary, but to keep it as long as possible to yield maximal signal.

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