MR and Proton MR Spectroscopy Findings of a Pediatric Case with Solitary Intracranial Rosai-Dorfman Disease in the Posterior Fossa
Sehnaz Tezcan1, Muhtesem Agildere1, Taner Sezer2, Ozge Ozturk1, and Aydın Sav3
1Radiology, Baskent University Hospital, Ankara, Turkey, 2Pediatrics, Division of Neurology, Baskent University Hospital, Ankara, Turkey, 3Pathology, Acıbadem Maslak Hospital, Istanbul, Turkey
Rosai-Dorfman disease (RDD) is a histioproliferative
disorder, rarely affects central nervous system. A 5-year old boy presented with ptosis,
diplopia. MR revealed enhancing mass in the cerebellar pedincle and pons. MR
Spectroscopy (MRS) of the lesion showed increased Choline/N-acetyl aspartate
ratio and lactate peak.. Histopathology was compatible with RDD. Although
intracranial RDD generally presents as dural based lesions and supratentorial
in location, intraparencymal lesions may be seen.. In this case report a rare
form of RDD, posterior fossa parenchyma involvement presented with particular
interest to brain MR, MRS and diffusion findings.
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