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Abstract #1345

Can dynamic contrast enhanced MR perfusion metrics accurately discriminate different grades of Gliomas?

Jitender Saini 1, Pradeep Kumar Gupta2, Prativa Sahoo3, Rana Patir4, Sandeep Vaishya5, Arun Kumar Gupta1, Amey Savarderkar6, and Rakesh Kumar Gupta2

1Neuroimaging & Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India, 2Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, 3Healthcare, Philips India ltd, Bangalore, India, 4Neuorsurgury, Fortis Memorial Research Institute, Gurgaon, India, 5Neuorsurgury, Fortis Memorial Research Institute, Lucknow, India, 6Neuorsurgury, National Institute of Mental Health and Neurosciences, Bangalore, India

Dynamic contrast enhanced MRI perfusion is a useful technique for assessment of glioma grading. This technique has been used in the past for discrimination of low from high grade gliomas. This study investigates the ability of DCE perfusion MRI to discriminate Grade II from Grade III and Grade III from Grade IV gliomas. Various DCE pharmacokinetic parameters were also analysed for their ability to distinguish the various grades of gliomas.

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