Intracranial aneurysm wall permeability: a potential risk predictor for rupture
Qi Haikun1, Peng Liu2, and Huijun Chen1
1Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, 2Department of Neurosurgical, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Beijing, China, People's Republic of
The rupture risk prediction of unruptured intracranial
aneurysm (IA) is very important in clinical practice and increased knowledge of
predictors for IA rupture is needed. IA wall permeability has great potential
for aneurysm rupture risk prediction, and can be quantified by DCE-MRI. In this
study, we measured IA wall permeability using DCE-MRI, and compared it with
established clinical/imaging risk metrics. We found IA wall permeability may be
independent of aneurysm size and IA wall enhancement providing distinctive information
for IA rupture risk prediction.
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