Dong-Hoon Lee1, Xuna Zhao1, Hye-Young Heo1, Yi Zhang1, Shanshan Jiang1, and Jinyuan Zhou1
MRI is a novel imaging technique to provide in
vivo image contrasts related with the changes of endogenous mobile amide
proton concentration and/or tissue pH. In this abstract, based on the
quantified APT signals and multi-parametric MR images, we attempted to evaluate
signal changes in transient focal ischemia in rat models. Our results clearly
showed that the APT imaging can be a useful technique to predict the ischemia
reperfusion status, and to provide the quantitative results more accurately.