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Abstract #1487

A Perfusion Phantom for Arterial Spin Labeled MRI

Hyo Min Lee1,2, Marta Vidorreta3,4, Yulin Vince Chang3, and John Alan Detre3,4

1Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, 2Institute for Biomedical Engineering, University and ETH Zürich, Zürich, Switzerland, 3Radiology, University of Pennsylvania, Philadelphia, PA, United States, 4Neurology, University of Pennsylvania, Philadelphia, PA, United States

ASL MRI is an appealing biomarker for clinical research and management, but ASL MRI sequences are difficult to calibrate because a reliable phantom for simulating tissue-specific perfusion has yet to be developed. In this work, we describe a prototype perfusion phantom based on 3D printed vessels and mock parenchyma that may allow reliable, ex-vivo assessments of ASL sequences.

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