Comparison of post mortem and
in vivo MR images requires an understanding of the temperature dependence of
the NMR parameters that generate relevant image contrast. Here, we therefore
evaluated the temperature dependence of the susceptibility and relaxivity of
ferritin-doped agar. A phantom containing cylinders doped with different
ferritin concentrations was scanned at 7T at temperatures ranging from 5–35⁰C.
R1, R2* and field maps were generated and the variation of each parameter with
ferritin concentration was evaluated. The variations of susceptibility, R2* and
R1 with ferritin concentration all decreased with increasing temperature with
R2* showing the strongest temperature dependence.