Histogram
analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could
be a promising quantitative approach in assessing tumour heterogeneity. We
retrospectively studied thirty-five treatment-naïve patients with cervical
cancer who had IVIM MRI examinations to determine to the value of IVIM
histogram analysis, as a means of assessing tumour heterogeneity, in
relationship with clinical staging. We observed statistically significant
differences in most histogram parameters of f
(perfusion fraction) between patients with early and locally advanced disease
but only three histogram parameters of D (true diffusion coefficient) were
statistically different in patients with early and locally advanced cervical
cancer.
