James Brittin1, Elizabeth Sadowski1, Kristin Bradley2, and Jessica Robbins1
1Radiology, University of Wisconsin, Madision, WI, United States, 2Radiation Oncology, University of Wisconsin, Madision, WI, United States
In our study of patients with cervical cancer, after initial treatment,
tumors that recurred tended to have a higher heterogeneity on BOLD R2* maps, and tended to have a positive
skew in their image histogram. As tumors undergo treatment, the AUC and skewness
decreases significantly. Our findings indicate that BOLD MRI texture analysis can
be used to assess long-term response to therapy after initial treatment and to
follow tumors during treatment. Further
studies using BOLD MRI texture analysis in cervical
cancer may help elucidate the utility of this technique in the course of
treatment of women with cervical cancer.
