Juan C. Camacho1,2, Nima Kokabi1, Peter A. Harri1, Tracy E. Powell2, and Sherif G. Nour1,2
1Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, 2Interventional MRI Program, Emory University Hospital, Atlanta, GA, United States
The
study objective is to investigate
Magnetic Resonance
Spectroscopic Imaging (1H-MRSI) in prostate lesions and to correlate the values
with the results of MRI-guided prostate targeted sampling. A prospective cohort
of patients presenting
with persistently elevated or rising serum prostate specific antigen (PSA) and
at least one lesion suspicious for prostate cancer that underwent MRI guided
targeted biopsy was evaluated. Thirty-five consecutive patients were recruited presenting with 179
suspicious lesions. ROC curve analysis
demonstrates a poor performance of 1H-MRSI as a non-invasive imaging biomarker.
