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Abstract #1644

Multi-Institution Liver Mass Evaluation at 1.5 and 3 T Using Free breathing, Through-time Spiral GRAPPA and Quantitative Perfusion

Shivani Pahwa1, Hao Liu2, Yong Chen3, Sara Dastmalchian1, Ziang Lu1, Chaitra Badve4, Alice Yu1, Joshua Batesole4, Hamid Chalian4, Katherine Wright1, Shengxiang Rao5, Caixia Fu6, Ignacio Vallines7, Dean Nakamoto8, Mark Griswold9, Nicole Seiberlich10, Zeng Mengsu11, and Vikas Gulani12

1Radiology, Case Western Reserve University, Cleveland, OH, United States, 2Zhongshan Hospital, Fudan University, Shanghai, China, People's Republic of, 3Case Western Reserve University, Cleveland, OH, United States, 4Radiology, University Hospitals, Cleveland, OH, United States, 5Zhongshan Hospital< Fudan University, Shanghai, China, People's Republic of, 6Siemens, Shanghai, China, People's Republic of, 7Siemens Healthcare, Shanghai, China, People's Republic of, 8Radiology, Case Western Reserve University and University Hospitals, Cleveland, OH, United States, 9Radiology and Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 10Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 11Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, People's Republic of, 12Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States

Breath holds and lack of a quantitative dimension are the two major challenges in liver MR imaging. Free breathing, perfusion sequences created in academic institutions in the developed world have not been tested in busy and overloaded radiology practices worldwide. We evaluated free-breathing, 3D Through-time Spiral GRAPPA perfusion technique at two different field strengths in the US and China. We found that the perfusion parameters obtained for two most common hepatic lesions ie hepatocellular carcinoma and metastases were remarkably consistent across sites, though statistically different according to pathology.

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