Meeting Banner
Abstract #1647

Predictive equations for abdominal fat depot volumes with MRI as reference in a multi-ethnic cohort of 4.5 year old Asian children

Suresh Anand Sadananthan1, Navin Michael1, Mya Thway Tint2, Kuan Jin Lee3, Jay Jay Thaung Zaw2, Khin Thu Zar Hlaing2, Pang Wei Wei2, Lynette Pei-Chi Shek4, Yap Kok Peng Fabian5,6, Peter D. Gluckman1,7, Keith M. Godfrey8, Yap Seng Chong1,2, Melvin Khee-Shing Leow9,10, Yung Seng Lee1,4, Christiani Jeyakumar Henry9, Marielle Valerie Fortier11, and S. Sendhil Velan1,3

1Singapore Institute for Clinical Sciences, A*STAR, Singapore, 2Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 3Singapore BioImaging Consortium, A*STAR, Singapore, 4Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 5Department of Paediatric Endocrinology, KK Women’s and Children’s Hospital, Singapore, 6Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 7Liggins Institute, University of Auckland, Auckland, New Zealand, 8MRC Lifecourse Epidemiology Unit & NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, 9Clinical Nutrition Research Centre, Singapore Institute for Clinical Sciences, A*STAR, Singapore, 10Department of Endocrinology, Tan Tock Seng Hospital, Singapore, 11Department of Diagnostic and Interventional Imaging, KK Women’s and Children’s Hospital, Singapore

Longitudinal assessment of abdominal fat compartments in children can help delineate some of the early risk factors that can predispose an individual to high abdominal adiposity and insulin resistance. While accurate determination of abdominal fat can be achieved using CT or MRI, it is often not performed in large cohort studies involving young children due to radiation exposure, high costs or poor compliance with scan procedures. The goal of this work is to develop and validate predictive equations for abdominal fat compartments from anthropometric values with MRI-based abdominal fat volumes as reference in multi-ethnic cohort of 4.5 year-old Asian children.

This abstract and the presentation materials are available to members only; a login is required.

Join Here