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Abstract #1689

Structural and Functional Brain Alterations in Uremic restless legs syndrome patients: A Voxel-Based Morphometry and Functional Connectivity Study

DUN DING1, PENG LI2, Ji Xin Liu2, Xue Ying Ma2, and Ming Zhang2

1XI'AN JIAO TONG UNIVERSITY, XI'AN, China, People's Republic of, 2XI'AN, China, People's Republic of

To investigate the structure and function changes in the brain in uremic RLS patients using a resting-state function magnetic resonance imaging (fMRI) paradigm, we used A voxel-based morphometry(VBM) method and a seed-based method to find the abnormiy in end-stage kidney disease patients. Our results suggest that the characteristics of the connectivity changes may reflect the pathways involved in producing uremic RLS symptoms.

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