Bilateral amygdaloid functional connectivity in chronic alcoholics
Ylin Zhao1, Jun Chen2, and Hui Lin3
1Radiology, Renmin Hospital of Wuhan University, Wuhan, China, People's Republic of, 2Renmin Hospital of Wuhan University, Wuhan, China, People's Republic of, 3Healthcare,MR Research China, Beijing, China, People's Republic of
FC-MRI is a useful tool for examining functional relationships between the bilateral amygdaloid and whole brain regions. The
functional coordination of bilateral amygdala and cerebral cortex was enhanced,and
the functional coordination of bilateral amygdala and cerebellum was weakened.Amygdala may be involved in regulating the function of
fronto-cerebellar loops.Thus, this method shows promise as a tool for in vivo investigations of the functioning of human fronto-cerebellar circuitry. It is our hope that in future studies this technique may provide the opportunity to examine the integrity of networks involving the brain cerebellum inpatient groups with chronic alcoholics, a major goal of our research.
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