Jingwei Zhang1,2, Dong Zhou2, Thanh Nguyen2, Pascal Spincemaille2, Ajay Gupta2, and Yi Wang1,2
1Biomedical Engineering, Cornell University, New York, NY, United States, 2Radiology, Weill Cornell Medical College, New York, NY, United States
This study proposed a new post-processing algorithm with preconditioning and physiological constraints for QSM based CMRO2 mapping, which eliminated physiologically impossible OEF values and improved the robustness of the technique. Reproducibility of the proposed method was examined. Feasibility of hyperventilation as a more efficient blood flow challenge was also investigated.