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Abstract #1812

The Harmonized Human Connectome Protocol for Multi-Site Brain MRI Studies

Joshua M Kuperman1, Nathan S White1, Hauke Bartsch1, Matthew Middione2, Kun Lu3, Thomas Liu3, Terry Jernigan4, Ajit Shankaranarayanan2, and Anders M Dale1,5

1Radiology, University of California, San Diego, La Jolla, CA, United States, 2GE Healthcare, Menlo Park, CA, United States, 3Center for Functional Magnetic Resonance Imaging, University of California, San Diego, La Jolla, CA, United States, 4Center for Human Development, University of California, San Diego, La Jolla, CA, United States, 5Neurosciences, University of California, San Diego, La Jolla, CA, United States

The benefits of the advanced MRI protocols used in the Human Connectome Project have heretofore only been available on Siemens MRI scanners. We have designed a Connectome-like protocol, called the Harmonized Human Connectome Protocol, which can utilize MRI scanners from additional vendors, specifically GE and Philips. This protocol is particularly relevant for the Adolescent Brain and Cognitive Development Study, which aims to scan over 10,000 children ages 9-10 and follow them longitudinally for ten years. This abstract details the protocol for the GE MR750 scanner and outlines calibration and correction procedures which can be used to further reduce unwanted site/scanner effects.

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