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Abstract #1943

MR elastography of intracranial tumors: Initial experience with high-resolution imaging and nonlinear inversion

Curtis L Johnson1, Emily S Matijevich1,2, Emily D Cullum1,2, Matthew DJ McGarry3, Keith D Paulsen3, Bradley P Sutton1,4, Tracey M Wszalek1,2, and William C Olivero1,2

1Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Carle Neuroscience Institute, Carle Foundation Hospital, Urbana, IL, United States, 3Thayer School of Engineering, Dartmouth College, Hanover, NH, United States, 4Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

MR elastography has emerged as an important tool for presurgical evaluation of intracranial tumors. Due to the localized nature of the lesion properties of interest, there is a need for high-resolution MRE methods for characterizing tumors. Here we present our initial experience with MRE of intracranial tumors using a protocol based on high-resolution imaging and nonlinear inversion. We found that glial tumors are soft and have a generally low viscosity, while meningeal tumors are stiff and have a very low viscosity.

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