Abstract #1959

Identification of Myocardial Anisotropic Material Properties using Magnetic Resonance Elastography and the Finite Element Method

Renee Miller¹, Arunark Kolipaka², Vicky Wang³, Martyn Nash³, and Alistair Young¹

¹Anatomy with Radiology, University of Auckland, Auckland, New Zealand, ²Radiology, Biomedical Engineering and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, United States, ³Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

In this study, we examined the determinability of anisotropic stiffness parameters using finite element analysis simulations of harmonic steady-state wave behaviour. Two simulation experiments, of cylindrical phantom and left ventricular geometries, and one phantom experiment using magnetic resonance elastography (MRE) were carried out. The transversely isotropic material properties were determined using a least-squares optimisation algorithm by matching a modelled displacement field to the reference, or MRE, displacement field. The results showed that the parameters were uniquely identifiable even in the presence of noise.

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