Mariko Doai1, Naoko Tsuchiya1, Hisao Tonami1, and Osamu Tachibana2
1Radiology, Kanazawa Medical University, Kahoku, Japan, 2Neurosurgery, Kanazawa Medical University, Kahoku, Japan
purpose of this study is to evaluate the utility of histogram analysis of apparent
diffusion coefficient (ADC) value for distinguishing pituitary atypical
adenomas from typical adenomas.
ADC maps were reviewed using Ziostation2, and placed a 3D volume-of interest on
entire tumor were computed. Histogram parameters were then compared between
atypical adenomas (n=3) and typical adenomas (n=11). Skewness and kurtosis of
ADC histogram were significantly lower for atypical adenoma as compared with
typical adenoma. ADC histogram analysis on the basis of the entire tumor volume
can be useful in distinguishing atypical adenomas from typical adenomas.