Abstract #2118

An ultrasound compatible rat RF array for MRI guided high intensity focused ultrasound

Xiao Chen¹, Rou Li¹, Changjun Tie¹, Xiaoqing Hu¹, Xiaoliang Zhang^2,3, Chao Zou¹, Xin Liu¹, Hairong Zheng¹, and Ye Li¹

¹Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, CAS, Shenzhen, China, People's Republic of, ²Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ³UCSF/UC Berkeley Joint Graduate Group in Bioengineering, San Francisco, CA, United States

Due to MRI’s unique capability of providing accurate, non-invasive and real-time target localization and temperature monitoring, MRI guided high intensity focused ultrasound (HIFU) has been a critical modality for imaged guided thermal therapy. We propose a 3 channel ultrasound compatible rat array to obtain high resolution and homogeneous rat brain images at 3T for temperature monitoring. Phantom and in-vivo imaging experiments in temperature mapping demonstrate the capability of the proposed array to provide homogenous and high SNR images and temperature map in the whole rat brain at 3T, which provides the possibility to perform MRI guided HIFU treatment in-vivo.

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