Abstract #2185

Clinical-Scale, Stopped-flow 129Xe Hyperpolarizer Development

Aaron M. Coffey¹, Panayiotis Nikolaou¹, Kaili Ranta², Iga Muradyan³, Matthew S. Rosen⁴, Samuel Patz³, Michael J. Barlow⁵, Boyd M. Goodson², and Eduard Y. Chekmenev¹

¹Radiology, Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, ²Southern Illinois University, Carbondale, IL, United States, ³Brigham & Women's Hospital, Boston, MA, United States, ⁴Harvard University, Cambridge, MA, United States, ⁵University of Nottingham, Nottingham, United Kingdom

We report on the development of a first and second generation ¹²⁹Xe hyperpolarizers, capable of producing high (~25-90%) ¹²⁹Xe hyperpolarization at high Xe densities (up to 2000 Torr partial pressure), suitable for clinical and materials MRS/MRI applications.

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