Meeting Banner
Abstract #2251

An assessment of the repeatability and sensitivity of T2 mapping in low-grade cartilage lesions at 3 and 7 Tesla

Vladimir Juras1,2, Laurent Didier3, Vladimir Mlynarik1, Pavol Szomolanyi1, Stefan Zbyn1, Nicole Getzmann3, Joerg Goldhahn3, Stefan Marlovits4, and Siegfried Trattnig1,5

1Department of Biomedical Imaging and Image-Guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, 2Department of Imaging Methods, Institute for Measurement Science, Bratislava, Slovakia, 3Novartis Institutes for Biomedical Research, Basel, Switzerland, 4Department of Traumatology, Medical University of Vienna, Vienna, Austria, 5Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

An assessment of the reliability of T2 mapping was achieved with a 3D-TESS sequence in patients with cartilage lesions ICRS Grade I-II. Since low-grade cartilage lesions are not usually accompanied by collagen matrix remodeling, we tested the sensitivity of T2 to detect these lesions at 3 and 7T. It seems that the reproducibility of 3T T2 mapping is higher than that of 7T; however, the sensitivity of T2 mapping for the detection of low-grade cartilage lesions was greater at the ultra-high field. T2 mapping could be used in the future as a good alternative to cartilage biopsies in future clinical trials on new therapies aimed at cartilage regeneration.

This abstract and the presentation materials are available to members only; a login is required.

Join Here