Victor Adalid Lopez1, André Doering1, Sreenath Pruthviraj Kyathanahally 1, Christine S. Bolliger1, and Roland Kreis1
Diffusion weighted spectroscopy can provide
information on the diffusion of metabolites and the microstructure of brain tissue.
A method for simultaneous fitting of spectra related by mono-exponential
diffusion weighting is introduced, which is similar to simultaneous fitting of
a 2DJ or inversion recovery data set. As shown for simulated white matter data,
the method improves both, accuracy and precision of ADC estimation for all
metabolites. It is also illustrated with diffusion data obtained from human
gray matter at 3T.