Jan Weis1, Fredrik Rosqvist2, Joel Kullberg1, Ulf Risérius2, and Håkan Ahlström1
1Department of Radiology, Uppsala University, Uppsala, Sweden, 2Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
Proton MR spectroscopy of healthy human
liver was performed at 3 T MR scanner. The
purpose of this study was to estimate glycogen (Glycg), choline-containing
compounds (CCC), water, and lipid (-CH2-)n relaxation times T1, T2, and absolute concentration
of Glycg, CCC, and fat. Experiments were performed using multiple
breath-hold technique. Spectra were processed by LCModel.
T1 and T2 values were obtained by mono-exponential fitting
spectral intensities versus repetition or echo times. Quantification
of liver Glycg, CCC and lipids is important for understanding changes in lipid
and glucose metabolism due to metabolic disorders.