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Abstract #2478

A compact and easy to handle set-up for high quality MR Elastography of the breast.

Jurgen H Runge1, Jules L Nelissen2,3, Larry de Graaf2, Barbara Molenkamp4, Suzan van der Meij4, Klaas Nicolay2, Gustav J Strijkers3, Jaap Stoker1, Anneloes E Bohte1, Aart J Nederveen1, Ondrej Holub5, and Ralph Sinkus5

1Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Biomedical NMR, Eindhoven University of Technology, Eindhoven, Netherlands, 3Preclinical and Translational MRI, Academic Medical Center, Amsterdam, Netherlands, 4Surgery, Academic Medical Center, Amsterdam, Netherlands, 5Biomedical Engineering, King's College London, London, United Kingdom

Distinction between benign and malignant breast lesions remains difficult with conventional (dynamic) contrast-enhanced MRI. MR Elastography (MRE) can distinguish benign and malignant tissues based on their viscoelastic properties but breast MRE has not found widespread use in daily clinical practice, because of the complex equipment required and cumbersome data acquisition. Here we present a compact, easy to handle breast MRE set-up that allows the acquisition of high quality, artefact-free MRE data. This set-up was designed, built and tested at two different institutions in volunteers and a patient.

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