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Abstract #2483

Influence of fat suppression to evaluate T1 values in breast cancer: assessing the reliability of pharmacokinetic parameters

Kayu Takezawa1, Mariko Goto1, Koji Sakai1, Hiroyasu Ikeno1, Katsuhiko Nakatsukasa2, Hiroshi Imai3, and Kei Yamada1

1Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 2Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan, 3Siemens Japan K.K, Tokyo, Japan

The influence of fat suppression on T1 values and pharmacokinetic parameters in breast cancer were evaluated using a prototype Dixon-TWIST-VIBE technique. We measured T1 values of breast cancers on both fat suppression and not-fat suppression data sets and we calculated Ktrans values using same ROI that employed on T1 value measurements. Our result suggests that the fat suppression might influence T1 values in breast cancer, and reliability of Ktrans seemed inappropriate as an absolute value. On the other hand, the assessment of intra-patient Ktrans change might be feasible.

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