Kayu Takezawa1, Mariko Goto1, Koji Sakai1, Hiroyasu Ikeno1, Katsuhiko Nakatsukasa2, Hiroshi Imai3, and Kei Yamada1
1Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 2Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan, 3Siemens Japan K.K, Tokyo, Japan
The influence of fat suppression on T1
values and pharmacokinetic parameters in breast cancer were evaluated using a
prototype Dixon-TWIST-VIBE technique. We measured T1 values of breast cancers
on both fat suppression and not-fat suppression data sets and we calculated Ktrans
values using same ROI that employed on T1 value measurements. Our result
suggests that the fat suppression might influence T1 values in breast cancer,
and reliability of Ktrans seemed inappropriate as an absolute value.
On the other hand, the assessment of intra-patient Ktrans change
might be feasible.