Abstract #2489

Luminal water imaging: a novel MRI method for prostate cancer diagnosis

Shirin Sabouri¹, Silvia Chang^2,3, Richard Savdie⁴, Jing Zhang⁵, Edward Jones⁶, Larry Goldenberg^4,7, and Piotr Kozlowski^2,4,5,7

¹Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ²Radiology, University of British Columbia, Vancouver, BC, Canada, ³Vancouver General Hospital, Vancouver, BC, Canada, ⁴Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, ⁵UBC MRI Research Center, Vancouver, BC, Canada, ⁶Pathology, Vancouver General Hospital, Vancouver, BC, Canada, ⁷Vancouver Prostate Centre, Vancouver, BC, Canada

MR multi-exponential T₂ mapping can be used for extracting valuable information about tissue composition in prostate. Using this technique, the fractional volume of the luminal space in the prostatic tissue can be determined. Since tissue composition and the amounts of lumen differ between normal and cancerous tissues, this technique can be applied for detection of prostatic tumors. We have investigated the suitability of using MR multi-exponential T₂ mapping for detection and staging of prostate cancer. We have acquired and analyzed MR images of 11 patients, and concluded that this technique is highly sensitive and specific in detection of prostatic tumors.

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