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Abstract #2493

A Fast Method for Simultaneous ADC and T2 Mapping Using Spin Echo EPI Sequence

Minxiong Zhou1,2, Xu Yan3, Ming Deng4, Zan Ke4, Xiangde Min4, Caixia Fu5, Hui Liu3, Alto Stemmer6, and Liang Wang4

1Shanghai University of Medicine & Health Sciences, Shanghai, China, People's Republic of, 2Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University of Medicine, China, Shanghai, China, People's Republic of, 3MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China, Shanghai, China, People's Republic of, 4Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, People's Republic of, 5Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, People's Republic of, 6Siemens Healthcare, Erlangen, Germany

This study proposes a fast SE-EPI-based method to simultaneously acquire ADC and T2 maps using dataset with multiple b-values and multiple TE values, which can be acquired in around 3 minutes. This method was validated using a group of prostate data, showing that the T2 maps generated by the proposed method were comparable to those by a conventional TSE-based method. In addition, both T2 and ADC showed significant differences between prostate cancer and benign prostatic hyperplasia, indicating that joint usage of ADC and T2 mapping might potentially help in tumor differentiation in difficult cases in addition to ADC alone. Furthermore, this method is intrinsically free of registration and misalignment artifacts between ADC and T2 and can also be integrated with other diffusion models such as IVIM, DKI.

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