Li Zhang1,2, Mihaela Pop1,2, and Graham A Wright1,2
1Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Accurate characterization of infarct heterogeneity depends on high spatial resolution imaging1. This study was performed to evaluate
the use of an accelerated multi-contrast late enhancement acquisition (MCLE)2 with COmpressed Sensing with Edge Preservation
(COSEP) for isotropic spatial resolution imaging to improve characterization of infarct heterogeneity in the clinical setting. We have
shown that an isotropic resolution of 2.2mm could be achieved using an accelerated three-dimensional (3D) MCLE acquisition within
a single breath-hold in a patient study and the COSEP reconstruction provides improved characterization of infarct heterogeneity
compared to an alternative compressed sensing method.