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Abstract #2597

Monitoring the Disease Progression and Aortic Hemodynamics of Pediatric Bicuspid Aortic Valve Patients Using Longitudinal 4D Flow MRI

Michael Rose1, Emilie Bollache2, Kelly Jarvis2,3, Alex Barker2, Susanne Schnell2, Bradley Allen2, Joshua Robinson4,5, Michael Markl2,3, and Cynthia Rigsby1,2

1Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, 2Radiology, Northwestern University, Chicago, IL, United States, 3Biomedical Engineering, Northwestern University, Chicago, IL, United States, 4Pediatrics, Northwestern University, Chicago, IL, United States, 5Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States

Over the course of two 4D flow MRI studies (mean duration between studies: 19 months), 12 pediatric BAV patients were evaluated for any changes in aortic hemodynamics. Hemodynamics were characterized via visual grading of flow patterns, peak systolic velocity and regional mean wall shear stress. There were no significant changes in visual grading scores, peak systolic velocities or mean wall shear stress values between baseline and follow up studies suggesting little BAV disease progression during this time.

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