Yoon-Chul Kim1, Sung Mok Kim1, Sung-Ji Park1, and Yeon Hyeon Choe1
Recently there have been several studies of estimation
of extracellular volume (ECV) fraction from dynamic contrast enhanced (DCE) myocardial
perfusion images using a distributed parameter (DP) model. We apply the DP model to DCE perfusion
images acquired from a standard stress perfusion protocol, and demonstrate ECV measurements
in aortic stenosis (AS) patients (n=13) and hypertrophic
cardiomyopathy (HCM) patients (n=11). Preliminary
results from sector-wise analysis indicate 1) higher mean ECV values in HCM
patients than normal volunteers and AS patients and 2) lower mean blood flow
values in AS and HCM patients than those in normal volunteers.
