Travis DeSa1, Jeremy D Collins1, James C Carr1, Kai Lin1, and Michael Markl1
Myocardial perfusion using MRI has become a promising non-invasive method to evaluate myocardial ischemia in CVDs. However, assessment of CMR's effectiveness in differentiating regional myocardial perfusion in patients with CVD and comparison of regional myocardial perfusion indices to cardiac global functional parameters has not been thoroughly studied. We evaluated 12 volunteers and 9 cardiac transplant patients and found significant differences in segmental and average CMR perfusion, but little correlation between perfusion and global functional parameters. This weak correlation indicates that myocardial perfusion may be more sensitive to detect early changes in LV dysfunction before the onset of global functional impairment.