1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, 2Philips Healthcare, Guangzhou, China, People's Republic of, 3Philips Healthcare, HongKong, China, People's Republic of
induced encephalopathy is one of the most serious complications of radiotherapy
(RT) for treatment of nasopharyngeal carcinoma (NPC). In order to detect early
radiation-induced changes in gray matter (GM) and white matter (WM) of NPC
patients after RT, we recruited NPC patients before RT and after RT with
normal-appearing brain for MR T1ρ examination. We found abnormal microstructure
changes of WM had already happened in NPC patients after RT even when routine
MRI findings are negative. MR T1ρ imaging can be used to detect early
radiation-induced changes of WM following RT for NPC patients.
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