4D flow MR imaging for differentiation of pulmonary arterial hemodynamics in pre-capillary pulmonary hypertension
Hideki Ota1, Koichiro Sugimura2, Haruka Sato2, Yuta Urushibata3, Yoshiaki Komori3, Hiroaki Shimokawa2, and Kei Takase1
1Diagnostic Radiology, Tohoku University Hosipital, Sendai, Japan, 2Cardiovascular Medicine, Tohoku University Hosipital, Sendai, Japan, 3Research&Collaborations, Siemens Japan KK, Tokyo, Japan
Etiologies of pre-capillary
pulmonary hypertension may be associated with pulmonary arterial hemodynamics. This study included 64 patients (pulmonary
arterial hypertension [PAH], 25, chronic thromboembolic pulmonary hypertension
[CTEPH], 39) who underwent 4D flow and cardiac MR imaging. Backward flow ratio
and forward flow eccentricity in the pulmonary trunk as assessed by 4D flow MR and
several cardiac MR parameters were different between two diseases. After
controlling for age and mean pulmonary arterial pressure, backward flow ratio
was the strongest differentiator of PAH from CTEPH. 4D flow has a potential to visualize different
pulmonary arterial hemodynamics according to etiologies in pulmonary hypertension.
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