Abstract #2728

Multi-parametric MRI for predicting disease recurrence or death in breast cancer patients following neo-adjuvant chemotherapy.

Elizabeth Anne Maxine O'Flynn¹, Maria A Schmidt¹, David Collins¹, James D'arcy¹, and Nandita M deSouza¹

¹Cancer Research UK Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Sutton, United Kingdom

The aim of this pilot study was to explore whether functional MRI metrics from a multi-parametric acquisition can predict for disease recurrence or death in breast cancer following neo-adjuvant chemotherapy. 60 months after commencement of the study, a lower R2* value was found at baseline in the women who are alive and disease free, suggesting that these tumours were less hypoxic and better oxygenated than those who developed metastatic disease or died in the interim

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