Abstract #2733

Removing Silicone Artifacts in Diffusion-Weighted Breast MRI by Means of Shift-Resolved Spatiotemporally Encoding

Eddy Solomon¹, Noam Nissan², Rita Schmidt¹, Edna Furman-Haran³, Uriel Ben-Aharon⁴, and Lucio Frydman¹

¹Chemical Physics Department, Weizmann Institute of Science, Rehovot, Israel, ²Biological Regulation Department, Weizmann Institute of Science, Rehovot, Israel, ³Unit of Biological Services, Weizmann Institute of Science, Rehovot, Israel, ⁴Breast Surgery Unit, Meuhedet Clinic, Ashdod, Israel

A new ADC-mapping methodology based on SPatio-temporal ENcoding (SPEN) was applied to augmented breasts, organs possessing multiple spectral components. SPEN provides a robust single-shot alternative to echo-planar-imaging (EPI) in terms of overcoming B0-inhomogeneities, while being able to resolve—and thereby suppress—the contributions of different chemical sites. Diffusion SPEN measurements were carried out at 3T on healthy volunteers with silicone-implant augmentation and compared against SE-EPI counterparts, confirming SPEN’s ability to yield more reliable ADC maps, free from the dominant silicone signal contributions, in a single shot. This opens new screening possibilities for cancer detection in breast augmented patients.

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