Thanh D. Nguyen1, Pascal Spincemaille1, Sneha Pandya1, Susan A. Gauthier1, and Yi Wang1
The purpose of this study was to develop a
clinically feasible method for quantifying myelin and iron distribution in white matter lesions by
integrating absolute myelin water mapping using Fast
Acquisition using Spiral Trajectory and T2prep (FAST-T2) sequence with Quantitative Susceptibility Mapping (QSM).
Preliminary results from 8 healthy volunteers and 3 MS patients demonstrated the feasibility of the developed method.