Meeting Banner
Abstract #2927

Incorporation of prior knowledge of the signal behavior into the compressed sensing framework for accelerated acquisition in hyperpolarized gas diffusion MRI

Juan FPJ Abascal1,2, Manuel Desco1,2,3, and Juan Parra-Robles1,2

1Department of Bioengeering and Aerospace Engineering, Universidad Carlos III de Madrid, Madrid, Spain, 2Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, 3Centro de Investigación en Red de Salud Mental (CIBERSAM), Madrid, Spain

Diffusion MRI measurements using hyperpolarized gases are generally acquired during patient breath hold, which yields a compromise between achievable image resolution, lung coverage and number of b-values. In this work, we propose a novel method that incorporates the knowledge of the signal decay into the reconstruction (SIDER) to accelerate the acquisition of MR diffusion data by undersampling in both spatial and b-value dimensions. SIDER is assessed by restrospectively undersampling diffusion datasets of normal volunteers and COPD patients. Results suggest that accelerations of at least x7 are achievable with negligible effect in the estimates of diffusion parameters.

This abstract and the presentation materials are available to members only; a login is required.

Join Here