Abstract #2932

Prediction of Longitudinal FEV1 Decline in Smokers with Hybrid Hyperpolarized 3He MRI

Hooman Hamedani^1,2, Yi Xin¹, Stephen J Kadlecek¹, Heather Gatens¹, Maurizio Cereda³, Sarmad M Siddiqui^1,2, Mehrdad Pourfathi^1,4, Joseph Naji¹, Masaru Ishii⁵, and Rahim R Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, ³Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States, ⁴Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, PA, United States, ⁵Johns Hopkins University, Baltimore, MD, United States

Aside from the superior diagnostic power that HP gas MRI provides through imaging unique aspects of lung function, it is evident that the underlying mechanisms that lead to subsequently evident global changes in the lung function in future are detectable through regional and functional imaging using HP gas MRI.

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