Abstract #2938

Assessing Liver Fibrosis in Patients with Chronic Hepatitis B: Comparison of T1 Mapping with Gd-EOB-DTPA-enhanced 1.5T MRI, Aspartate Aminotransferase-to-Platelet Ratio Index and Fibrosis-4

Li Yang¹, Ying Ding², Mengsu Zeng³, Shengxiang Rao³, and Ruofan Sheng³

¹Shanghai Institute of Medical Imging, Zhongshan Hospital of Fudan University, Shanghai, China, People's Republic of, ²Zhongshan Hospital of Fudan University,Shanghai Institute of Medical Imging, Shanghai, China, People's Republic of, ³Zhongshan Hospital of Fudan University, Shanghai, China, People's Republic of

Hepatobiliary-phase gadoxetic acid-enhanced MR imaging may reflect liver function and was reported to be able to predict liver fibrosis stage with higher reliability. Aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis-4 (FIB-4) are widely used non-invasive tests that estimate liver fibrosis. We compared the diagnostic performance of T1 mapping on Gd-EOB-DTPA-enhanced 1.5T magnetic resonance imaging (MRI), APRI and FIB-4 for evaluating the severity of liver fibrosis in 118 patients with chronic viral hepatitis B, and the results showed The HBP T1 relaxation time measurement on gadoxetic acid-enhanced appears superior to unenhanced, D% (the reduction rate) of T1 relaxation times, the APRI and FIB-4 index in differentiating advanced liver fibrosis.

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