This paper is to discuss the impact of fat on
the Gd-based contrast behavior in a mixture of water based Gd-BOPTA solution
and fat. A set of vials, contains such mixtures with various fat fraction and
Gd-BOPTA concentration, was constructed and scanned using both Turbo Spin Echo
(TSE) with 3 point Dixon, and VIBE-Dixon. With VIBE-Dixon, the slopes of the
regression (relaxivity) of R1 vs. [Gd] in water were very close among groups
with various fat fraction; while with TSE image, the slopes of R1 vs. [Gd] in
whole mixture were close among vial groups.