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Abstract #2946

MRI-based Estimation of Liver Function by Intravoxel Incoherent Motion Diffusion-weighted Imaging

Jing Zhang1, Yikai Xu1, Yihao Guo2, Yanqiu Feng2, Queenie Chen3, Yingjie Mei2,4, Xiangliang Tan1, Jiajun Zhang1, Xixi Zhao1, Zeyu Zheng1, and Chunhong Wang1

1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, 2School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, People's Republic of, 3Philips Healthcare, Hong Kong, China, People's Republic of, 4Philips Healthcare, Guangzhou, China, People's Republic of

The quantitative evaluation of hepatic function is important for monitoring patients and preoperative assessment of the hepatic reserve. This work aims to assess the sensitivity of IVIM in evaluating liver function in patients with chronic liver disease. The results demonstrate that perfusion-related parameters (D* and f) are useful for indicating the severity of liver disease, and may have the potential to become a promising non-invasive tool for monitoring liver function.

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